Lost in the depths of the Peruvian Amazon is a vine that whispers secrets of existence. The shamans—traditional medicine men—are the keepers of these esoteric secrets, and they say this vine doesn’t reveal its wisdom easily.

Cue is a haven for tropical plant enthusiasts, with its great Victorian Palm House at the Royal Botanical Gardens. Piers Gibbon, an actor and an amateur ethnobotanist, dreams of finding a plant so unique it would bear his name at Kew. He’s fascinated by plants that speak to humanity, not in a literal sense, but through their effects when used as traditional medicine. His journey started in academia but took an adventurous turn toward direct experience with hallucinogenic plants.

Inspired by his obsessions, Piers turns his sights on the legendary ayahuasca, a potent brew used by Amazonian shamans. It’s a concoction that causes nausea but is famous for its intense, often terrifying visions that some claim hold healing powers. But ayahuasca isn’t one plant; it’s a mix. The key ingredient yapo vine works only when combined with chacruna leaves, which Piers now seeks.

Traveling to Iquitos, the gateway to the Peruvian Amazon, Piers connects with Alan Shoemaker, who introduces tourists to ayahuasca. But what Piers experiences is more than just a touristy thrill—it’s an initiation into a deeper layer of human consciousness.

Guided by Alan, he endures purging rituals and hallucinatory nights to understand why these plants have fascinated him for so long. Suddenly, the adventure gets a practical twist—searching for the elusive chacruna plant. This quest takes Piers deeper into the Amazon, accompanied by guides like Richard Fowler and anthropologists knowledgeable in tribal practices.

In a Matses village, Piers encounters another dimension of traditional Amazonian medicine—frog poison, or sapo, used for its purgative and spiritually cleansing effects. The indigenous people rely on these practices not just for mystical experiences but for practical, everyday strength and wisdom.

Even as he gets closer to his goal, Piers realizes that understanding ayahuasca and its spiritual uses is a profound journey. With each step deeper into the jungle, he meets more shamans, experiences more rituals, and grapples with the powerful psychological effects of the substances.

Eventually, Piers finds more than he bargained for—his quest leads him to Don Dimetrio, a shaman with a deep understanding of ayahuasca’s power. After intense ceremonies and a period of solitude in the jungle, Piers is offered a final, life-changing ritual. Don Dimetrio offers him a substance that would bind him spiritually, a rare gift signaling ultimate trust.

Piers’s story winds up with a tangible achievement—he finds the chacruna plant and collects it for the Royal Botanical Gardens. But more significantly, he gains a deeper understanding of himself and the mystical plants that captured his curiosity in the first place.

In the end, Piers’s journey is not just about collecting plants for scientific study; it’s about an intense, personal metamorphosis that challenges and reshapes his sense of purpose and identity.